While there are many ways to treat estrogen-deficient skin, such as hormone replacement therapy, if you are more interested in superficial treatments, topical products can help address them. Estrogen-deficient skin is fragile, so consider adding gentle hydrating cleansers and collagen-stimulating products to your regime. Rich moisturizers may also help create a barrier to protect your skin, and sunscreen is imperative. Estrogen-deficient skin cannot defend itself as efficiently as younger skin, so UV protection is an absolute must. Lastly, you should consult your doctor if you have concerns about your estrogen levels or hormonal fluctuations.