There’s nothing more annoying than makeup that begins to pill seconds after applying it. Thankfully, there are ways to prevent it from happening in the future! First of all, foundation pilling is often caused by moisturizers and foundations reacting to each other. To prevent this from happening, wait 5 minutes after moisturizing before applying makeup. If pilling continues, you may be mixing incompatible ingredients, such as water-based products with silicone or oil-based products.