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Wondering when you should apply acne spot treatments in your skincare routine? According to skin experts, as a general rule, spot treatments should be applied after you cleanse and tone your skin but before serums and other creams. This is because the ingredients contained in spot treatments are most effective when applied to clean skin.
Additionally, when you use a spot treatment on top of a thicker cream or oil, it may get diluted or not penetrate as well as it should. However, if your spot treatment is drying or irritating, you should apply a thin layer of moisturizer before applying your spot treatment to help minimize any adverse effects.